3-Amino-1,2-propanediol → HCID 18433128, compound

HRID 2305533Notes

Reaction equation

HRID 2305533 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([OH:12])[CH:10]=2)[N:5]=[C:4]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:3]=1.[NH2:19][CH2:20][CH:21]([OH:24])[CH2:22][OH:23]>>[ClH:1].[OH:12][C:9]1[CH:10]=[C:11]2[C:6](=[CH:7][CH:8]=1)[N:5]=[C:4]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[CH:3]=[C:2]2[NH:19][CH2:20][CH:21]([OH:24])[CH2:22][OH:23]

Participants

3

Reactant 2

HCID 735613-Amino-1,2-propanediolHCID 18432940HCID 18432940, compound

Product 1

HCID 18433128HCID 18433128, compound

Procedure

The title compound, m.p. 303-304° C., and MS: m/e=310 (M+), was prepared from 4-chloro-2-phenyl-quinolin-6-ol and (RS)-3-amino-1,2-propandiol.

Sources & evidence

ORD record
ord-7cf9aeeae6e84a248952e3927021ae48
Source dataset
uspto-grants-2002_08
Patent number
US06440995B1

Reaction notes

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