3-Amino-1,2-propanediol → HCID 18432934, compound

HRID 2305534Notes

Reaction equation

HRID 2305534 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH:3]=1.[NH2:18][CH2:19][CH:20]([OH:23])[CH2:21][OH:22]>>[ClH:1].[C:12]1([C:4]2[CH:3]=[C:2]([NH:18][CH2:19][CH:20]([OH:23])[CH2:21][OH:22])[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[N:5]=2)[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Participants

3

Reactant 2

HCID 735613-Amino-1,2-propanediolHCID 2783764-chloro-2-phenylquinoline

Product 1

HCID 18432934HCID 18432934, compound

Procedure

The title compound, m.p. 225-227° C., and MS: m/e=295.3 (M+H+), was prepared from 4-chloro-2-phenyl-quinolin and (RS)-3-amino-1,2-propandiol.

Sources & evidence

ORD record
ord-de9f6b31192d4983bff5db163c2c9ddf
Source dataset
uspto-grants-2002_08
Patent number
US06440995B1

Reaction notes

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