3-Amino-1,2-propanediol → HCID 18432929, compound

HRID 2305536Notes

Reaction equation

HRID 2305536 reaction equation
[S:1]1[C:5]([C:6]2[CH:15]=[C:14]([Cl:16])[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[N:7]=2)=[CH:4][C:3]2[CH:17]=[CH:18][CH:19]=[CH:20][C:2]1=2.[NH2:21][CH2:22][CH:23]([OH:26])[CH2:24][OH:25]>>[ClH:16].[S:1]1[C:5]([C:6]2[CH:15]=[C:14]([NH:21][CH2:22][CH:23]([OH:26])[CH2:24][OH:25])[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[N:7]=2)=[CH:4][C:3]2[CH:17]=[CH:18][CH:19]=[CH:20][C:2]1=2

Participants

3

Reactant 2

HCID 735613-Amino-1,2-propanediolHCID 18433048HCID 18433048, compound

Product 1

HCID 18432929HCID 18432929, compound

Procedure

The title compound, m.p. 253-255° C., and MS: m/e=386 (M+), was prepared from 2-benzo[b]thiophen-2-yl-4-chloro-quinoline and (RS)-3-amino-1,2-propandiol.

Sources & evidence

ORD record
ord-90f1901d997e40c880e10fe3c8a71e43
Source dataset
uspto-grants-2002_08
Patent number
US06440995B1

Reaction notes

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