3-Amino-1,2-propanediol → HCID 18433046, compound

HRID 2305540Notes

Reaction equation

HRID 2305540 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([N+:12]([O-:14])=[O:13])[CH:10]=2)[N:5]=[C:4]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH:3]=1.[NH2:21][CH2:22][CH:23]([OH:26])[CH2:24][OH:25]>>[ClH:1].[N+:12]([C:9]1[CH:10]=[C:11]2[C:6](=[CH:7][CH:8]=1)[N:5]=[C:4]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)[CH:3]=[C:2]2[NH:21][CH2:22][CH:23]([OH:26])[CH2:24][OH:25])([O-:14])=[O:13]

Participants

3

Reactant 2

HCID 735613-Amino-1,2-propanediolHCID 15621416HCID 15621416, compound

Product 1

HCID 18433046HCID 18433046, compound

Procedure

(RS)-3-(6-Nitro-2-phenyl-quinolin-4-ylamino)-propane-1,2-diol hydrochloride was prepared according to the general procedure described in example 1 from 4-chloro-6-nitro-2phenyl-quinoline and (RS)-3-amino-1,2-propandiol.

Sources & evidence

ORD record
ord-a4095b9746a0479fbf7cdd786a48967d
Source dataset
uspto-grants-2002_08
Patent number
US06440995B1

Reaction notes

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