反应详情

To methyl 2-phenylaminobenzoxazole-6-acetate (0.28 g) in a mixture of dimethyl sulphoxide (1 ml) and tetrahydrofuran (1 ml) was added 2M sodium hydroxide (1 ml). The mixture was stirred for 2 hrs. then acidified with acetic acid and diluted with water and the precipitate filtered and washed with water and dried to give 2-phenylaminobenzoxazole-6-acetic acid (0.24 g) as a white solid.

1. filtrationthe precipitate filtered
2. washwashed with water
3. customdried