反应详情

温度

50 °C

A suspension of 133 mg (0.57 mmol) of ethyl 7-nitroindole-2-carboxylate in 3.84 ml of 28% aqueous ammonia is heated at 50° C. for 18 h in a stoppered glass tube. The reaction medium is filtered over sintered glass. The yellow solid obtained is washed with water and with cyclohexane and then dried under vacuum. 70 mg of 7-nitro-1H-indole-2-carboxamide are obtained in the form of a yellow solid.

1. filtrationThe reaction medium is filtered over sintered glass
2. customThe yellow solid obtained
3. washis washed with water and with cyclohexane
4. customdried under vacuum