HCID 14940862, compound → 4-cyclopentylpentanoic acid

HRID 2305940Notes

Reaction equation

HRID 2305940 reaction equation
[C:1]1(=[C:6]([CH3:12])[CH2:7][CH2:8][C:9]([OH:11])=[O:10])[CH:5]=[CH:4][CH:3]=[CH:2]1>C(OCC)(=O)C>[CH:1]1([CH:6]([CH3:12])[CH2:7][CH2:8][C:9]([OH:11])=[O:10])[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 1

HCID 14940862HCID 14940862, compound

Product 1

HCID 2288754-cyclopentylpentanoic acidYield 92.4%

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

4-Cyclopenta-2,4-dienylidenepentanoic acid (25 g; 0.15 mol; obtained according to Coe, J. W.; Vetelino, M. G.; Kemp, D. S., Tetrahedron Lett., 1994, 35, 6627.) in ethyl acetate (270 ml) was hydrogenated as in example 4 to give 23.6 g (92% yield) of crude 4-cyclopentylpentanoic acid which was used in the next step without further purification.

Sources & evidence

ORD record
ord-3e30225dba9149a29bd407461a95f152
Source dataset
uspto-grants-2002_08
Patent number
US06441052B1

Reaction notes

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