HCID 69967032, compound → HCID 69968615, compound

Participants

Reaction Steps

4-(4-Amino-2,6-dimethyl-phenoxy)-2-cyclopropylmethanesulfonyl-phenol was prepared from 2-cyclopropylmethanesulfonyl-4-(2,6-dimethyl-4-nitro-phenoxy)-phenol according to a procedure analogous to that described in EXAMPLE 4, Step A. Methanol was used instead of ethanol as a co-solvent. Reaction mixture was hydrogenated for 3 hours. After the mixture was filtered through Celite® and concentrated, the title product of Step D was used in the next step without purification. MS (APCI−) Calc.: 347.4, Found: 346.0 (M−1).

Provenance & Evidence