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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2306004Generated: October 31, 2026

Hydrochloric Acid → HCID 49801998, compound

https://huagongshe.com/reaction/2306004

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactantmethyl (S)-phenyl((R)-piperidin-2-yl)acetateHCID 6101852—
SolventWaterHCID 962—
ProductHCID 49801998HCID 49801998—

Reaction Steps

A solution of dl-threo-methylphenidate (1 g) in water (25 ml) and conc. HCl (5 ml) was heated under reflux for 3 h. The clear solution was evaporated to dryness, to give a dl-threo-ritalinic acid hydrochloride as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06441178B2
Source datasetuspto-grants-2002_08
ORD IDord-5b6f91eaed9743fca4c2f329b3aea8d3
Source noteuspto-grants-2002_08