Hydrochloric Acid → HCID 178500033, compound

HRID 2306219Notes

Reaction equation

HRID 2306219 reaction equation
[ClH:1].[NH:2]1[CH:6]=[C:5]([CH:7]=[CH:8][C:9]([OH:11])=[O:10])[N:4]=[CH:3]1.Cl.[CH3:13]O>>[ClH:1].[NH:2]1[CH:6]=[C:5]([CH:7]=[CH:8][C:9]([O:11][CH3:13])=[O:10])[N:4]=[CH:3]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 178479755HCID 178479755, compound

Product 1

HCID 178500033HCID 178500033, compound

Procedure

A solution of 4-imidazoleacrylic acid hydrochloride (20.0 g, 145 mmol) in MeOH (300 mL) was saturated with HCl (g). The resulting solution was refluxed for 90 min., then concentrated to dryness in vacuo to afford the titled ester as a white solid.

Workup

  1. temperatureThe resulting solution was refluxed for 90 min.
  2. concentrationconcentrated to dryness in vacuo

Sources & evidence

ORD record
ord-2d94d79ec0bf4f4992740d78f8c5f808
Source dataset
uspto-grants-2002_08
Patent number
US06441017B1

Reaction notes

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