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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2306257Generated: November 2, 2026

HCID 70172693, compound → HCID 178454138, compound

https://huagongshe.com/reaction/2306257

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 70172693HCID 70172693—
SolventAcetic AcidHCID 176—
ProductHCID 178454138HCID 178454138—

Reaction Conditions

Temperature120 °C

Reaction Steps

(S)-3-(tert-Butoxycarbonylamino)-1-(2-methoxyquinolin-8-yl)-2-oxopyrrolidine, as described above in Step F, (287 mg, 0.803 mmol) and KI (240 mg, 1.44 mmol) were dissolved in AcOH (10 mL) and heated to 120° C. for 1 hour. The reaction mixture was concentrated in vacuo, to yield the above-titled compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06441017B1
Source datasetuspto-grants-2002_08
ORD IDord-59f021395f0d4f80ab64c93e904bc553
Source noteuspto-grants-2002_08