N-Methylbenzylamine → N-methyl-N-(phenylmethyl)-2-{4-[3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl]phenyl}acetamide

Participants

Role	Name	HCID	Charge
Reactant	N-Methylbenzylamine	HCID 7669	—
Reactant	{4-[3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl]phenyl}acetic acid	HCID 50992931	—
Product	N-methyl-N-(phenylmethyl)-2-{4-[3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl]phenyl}acetamide	HCID 24827047	—

Reaction Steps

The title compound was prepared from {4-[3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl]phenyl}acetic acid and N-methylbenzylamine using a similar procedure to that described for Example 13, but purified by flash column chromatography eluting from 0-66% ethyl acetate in hexane.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07566735B2
Source dataset	uspto-grants-2009_07
ORD ID	ord-711205033b0d4040a21bec670e0e6b5d
Source note	uspto-grants-2009_07