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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 230670Generated: October 31, 2026

3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazole → 1-{4-[1-(1-pyrrolidinylcarbonyl)cyclopropyl]phenyl}-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazole

https://huagongshe.com/reaction/230670

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazoleHCID 2802863—
Reactant1-{[1-(4-Iodophenyl)cyclopropyl]carbonyl}pyrrolidineHCID 57762828—
Product1-{4-[1-(1-pyrrolidinylcarbonyl)cyclopropyl]phenyl}-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazoleHCID 24827142—

Reaction Steps

The title compound was prepared from 1-{[1-(4-iodophenyl)cyclopropyl]carbonyl}pyrrolidine and 3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazole using a similar procedure to that described for Example 19.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07566735B2
Source datasetuspto-grants-2009_07
ORD IDord-fae2ec22b498425e9bc3dd8cf284f9f9
Source noteuspto-grants-2009_07