Sulfuric acid magnesium salt (1:1) → HCID 22610274, compound

HRID 2306814Notes

Reaction equation

HRID 2306814 reaction equation
C([O:3][C:4]([C:6]1[NH:10][C:9]2[CH:11]=[C:12]([CH:14]=[O:15])[S:13][C:8]=2[CH:7]=1)=[O:5])C.[O-]S([O-])(=O)=O.[Mg+2]>C(OCC)(=O)C>[CH:14]([C:12]1[S:13][C:8]2[CH:7]=[C:6]([C:4]([OH:5])=[O:3])[NH:10][C:9]=2[CH:11]=1)=[O:15]

Participants

4

Reactant 2

HCID 24083Sulfuric acid magnesium salt (1:1)HCID 13012859HCID 13012859, compound

Product 1

HCID 22610274HCID 22610274, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

2-Formyl-4H-thieno[3,2-b]pyrrole-5-carboxylic acid ethyl ester (see, for example, Gale, W. W. et al., J. Org. Chem., 29: 2160-2165 (1964)) was hydrolyzed according to Procedure F (50° C. overnight; acidified aqueous phase extracted with ethyl acetate; combined organic phases dried over MgSO4, concentrated).

Sources & evidence

ORD record
ord-62c353965063472a93c43636f1154e52
Source dataset
uspto-grants-2004_12
Patent number
US06828343B2

Reaction notes

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