Potassium Carbonate → HCID 10150480, compound

HRID 2306874Notes

Reaction equation

HRID 2306874 reaction equation
C([O:4][C:5]([CH3:28])([CH3:27])[C:6]([NH:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[S:15][CH2:16][C:17]1[C:25]([Cl:26])=[CH:24][C:20]2[O:21][CH2:22][O:23][C:19]=2[CH:18]=1)=[O:7])(=O)C.C(=O)([O-])[O-].[K+].[K+]>CO>[Cl:26][C:25]1[C:17]([CH2:16][S:15][C:10]2[CH:11]=[CH:12][CH:13]=[CH:14][C:9]=2[NH:8][C:6](=[O:7])[C:5]([OH:4])([CH3:27])[CH3:28])=[CH:18][C:19]2[O:23][CH2:22][O:21][C:20]=2[CH:24]=1

Participants

4

Reactant 2

HCID 11430Potassium CarbonateHCID 10287885HCID 10287885, compound

Product 1

HCID 10150480HCID 10150480, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The material from Example 20 was treated with potassium carbonate in methanol overnight. The solvent was evaporated under a stream of nitrogen and the residue chromatographed on silica to give the title product. MS (ESI+) for C18H18ClNO4S m/z 380 (M+H)+.

Workup

  1. customThe solvent was evaporated under a stream of nitrogen
  2. customthe residue chromatographed on silica

Sources & evidence

ORD record
ord-b752da1e6d7d41af82c2831eb83ef4ad
Source dataset
uspto-grants-2004_12
Patent number
US06828446B2

Reaction notes

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