HRID2306882

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID14797

Potassium hydroxide

HKO

$结构：COC(=O)C(C)(/C=C\CC#N)NC(=O)OC(C)(C)C$

HCID86585310

未命名化合物

PRODUCTS

生成物

$结构：CC(C)(C)OC(=O)NC(C)(/C=C\CC#N)C(=O)[O-].[K+]$

HCID23689684

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID962

Water

H2O

CONDITIONS

反应条件

温度: 50 °C

PROCEDURE

实验过程

The methyl (3Z)-2-[(tert-butoxycarbonyl)amino]-5-cyano-2-methylpent-3-enoate product of Example 1d is taken up in DI water. To this is added KOH and the reaction mixture is stirred at 50° C. for 3 h. It is then concentrated under reduced pressure to give the desired title product.

WORKUP

后处理

concentrationIt is then concentrated under reduced pressure