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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2306882Generated: November 1, 2026

Potassium Hydroxide → (3z)-2-[(Tert-butoxycarbonyl)amino]-5-cyano-2-methylpent-3-enoic acid potassium salt

https://huagongshe.com/reaction/2306882

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium HydroxideHCID 14797—
ReactantMethyl (3Z)-2-[(tert-butoxycarbonyl)amino]-5-cyano-2-methylpent-3-enoateHCID 86585310—
SolventWaterHCID 962—
Product(3z)-2-[(Tert-butoxycarbonyl)amino]-5-cyano-2-methylpent-3-enoic acid potassium saltHCID 23689684—

Reaction Conditions

Temperature50 °C

Reaction Steps

The methyl (3Z)-2-[(tert-butoxycarbonyl)amino]-5-cyano-2-methylpent-3-enoate product of Example 1d is taken up in DI water. To this is added KOH and the reaction mixture is stirred at 50° C. for 3 h. It is then concentrated under reduced pressure to give the desired title product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06828456B2
Source datasetuspto-grants-2004_12
ORD IDord-a7c492f0292a424f947c1736dbaf5101
Source noteuspto-grants-2004_12