HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2306883Generated: October 31, 2026
Hydrochloric Acid → (3Z)-2-amino-5-cyano-2-methylpent-3-enoic Acid Hydrochloride
https://huagongshe.com/reaction/2306883
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | (3z)-2-[(Tert-butoxycarbonyl)amino]-5-cyano-2-methylpent-3-enoic acid potassium salt | HCID 23689684 | — |
| Solvent | Water | HCID 962 | — |
| Product | (3Z)-2-amino-5-cyano-2-methylpent-3-enoic Acid Hydrochloride | HCID 9942357 | — |
Reaction Steps
The (3Z)-2-[(tert-butoxycarbonyl)amino]-5-cyano-2-methylpent-3-enoic acid potassium salt product of Example 1j is taken up in DI water (80 mL) containing HCl. The reaction mixture is stirred at 50° C. for 2 h. and concentrated on a rotary evaporator to give the crude product. It is purified using a Gilson chromatographic system to provide the desired title product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06828456B2 |
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| Source dataset | uspto-grants-2004_12 |
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| ORD ID | ord-38dbc211c68f4fb4b56bb943aef3e8e3 |
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| Source note | uspto-grants-2004_12 |
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