反应详情

温度

50 °C

The (3Z)-2-[(tert-butoxycarbonyl)amino]-5-cyano-2-methylpent-3-enoic acid potassium salt product of Example 1j is taken up in DI water (80 mL) containing HCl. The reaction mixture is stirred at 50° C. for 2 h. and concentrated on a rotary evaporator to give the crude product. It is purified using a Gilson chromatographic system to provide the desired title product.

1. concentrationconcentrated on a rotary evaporator
2. customto give the crude product
3. customIt is purified