3-Azido-1,5,5-trimethyl-1-cyclohexene → HCID 22630126, compound

HRID 2307092Notes

Reaction equation

HRID 2307092 reaction equation
[N:1]([CH:4]1[CH2:9][C:8]([CH3:11])([CH3:10])[CH2:7][C:6]([CH3:12])=[CH:5]1)=[N+]=[N-].[ClH:13].C(C1(N)CC(C)(C)CC(C)(C)C1)C=C>>[ClH:13].[CH3:12][C:6]1[CH2:7][C:8]([CH3:11])([CH3:10])[CH2:9][CH:4]([NH2:1])[CH:5]=1

Participants

3

Reactant 2

HCID 108882753-Azido-1,5,5-trimethyl-1-cyclohexeneHCID 22630118HCID 22630118, compound

Product 1

HCID 22630126HCID 22630126, compoundYield 57%

Procedure

Prepared from azide 34 according to the procedure for compound 11 (Example 3, c). Amine hydrochloride 35 obtained as a colorless solid in 57% yield. 1H NMR (CDCl3, TMS): 0.89 and 1.03 (total 6H, both s, 5,5-CH3); 1.25-2.15 (4H, m, 4,6-CH2); 1.72 (3H, s, 3-CH3); 3.88 (1H, m, 1-CH); 5.41 (1H, s, C═CH) and 8.40 ppm (3H, br s, NH3+).

Sources & evidence

ORD record
ord-f080e1c9d06b419b864eeae7d6376c08
Source dataset
uspto-grants-2004_12
Patent number
US06828462B2

Reaction notes

Loading…