HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 22605931, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Reactant | HCID 69896191 | HCID 69896191 | — |
| Product | HCID 22605931 | HCID 22605931 | — |
Reaction Steps
Following the general method described in example 9, 6-(3,4-dihydro-1H-isoquinolin-2-yl)-pyridine-2-carboxylic acid amide (example 22a) was reacted with lithium aluminum hydride. After workup and chromatography the free base of the title compound was treated with hydrogen chloride and crystallized as the off white salt. Mp. 192-195° C. (iPr2O), MS: m/e=239 (M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06831087B2 |
| Source dataset | uspto-grants-2004_12 |
| ORD ID | ord-ea826b4102004fc681a213fbab23ad78 |
| Source note | uspto-grants-2004_12 |