tert-Butoxy bis(dimethylamino)methane → HCID 69844287, compound

Participants

Reaction Steps

A reaction mixture of 1-[4-(5H,11H-pyrrolo[2,1-c][1,4]benzodiazepine-10-carbonyl)-phenyl]-ethanone (1.40 g), t-butoxy-bis-dimethylaminomethane (5.0 ml) and dichloromethane (10 ml) was stirred for 18 hours. The red-orange precipitate was filtered to yield the title compound (1.22 g), m.p. 203-205° C. Additional product (0.18 g) was isolated from the reaction mixture by concentration.

Provenance & Evidence