反应详情

14.3 500 mg of Raney nickel are added to a solution of 2.40 g (8.76 mmol) of methyl (3-amino-4-nitrobenzenesulfonyl)acetate in 50 ml of methanol, and the mixture is hydrogenated at room temperature and atmospheric pressure. The catalyst is filtered off, and the filtrate is evaporated, giving methyl (3,4-diaminobenzenesulfonyl)acetate as a yellow solid; ESI 245.

1. customis hydrogenated at room temperature
2. filtrationThe catalyst is filtered off
3. customthe filtrate is evaporated