Dimethylformamide dimethyl acetal → HCID 22605463, compound

HRID 2307376Notes

Reaction equation

HRID 2307376 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[C:11]([N:13]1[C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][C:18]=2[CH2:17][N:16]2[CH:24]=[CH:25][CH:26]=[C:15]2[CH2:14]1)=[O:12])[C:5]([NH2:7])=[O:6].CO[CH:29](OC)[N:30]([CH3:32])[CH3:31]>>[CH3:29][N:30]([CH:32]=[N:7][C:5](=[O:6])[C:4]1[CH:8]=[CH:9][C:10]([C:11]([N:13]2[C:19]3[CH:20]=[CH:21][CH:22]=[CH:23][C:18]=3[CH2:17][N:16]3[CH:24]=[CH:25][CH:26]=[C:15]3[CH2:14]2)=[O:12])=[C:2]([Cl:1])[CH:3]=1)[CH3:31]

Participants

3

Reactant 2

HCID 78373Dimethylformamide dimethyl acetalHCID 9969119HCID 9969119, compound

Product 1

HCID 22605463HCID 22605463, compound

Procedure

The title compound was prepared in the same manner as described in Example 80, employing 3-chloro-4-(5H,11H-pyrrolo[2,1-c][1,4]benzodiazepine-10-carbonyl)-benzamide (1.83 g) and dimethylformamide dimethylacetal (5.3 ml), MS (EI), m/z::420 (M)+.

Sources & evidence

ORD record
ord-04528a640af44306ac77497e943dfa70
Source dataset
uspto-grants-2004_12
Patent number
US06831079B1

Reaction notes

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