Ethyl chloroformate → HCID 69945511, compound

HRID 2307531Notes

Reaction equation

HRID 2307531 reaction equation
[C:1]([O:9][CH2:10][C@H:11]1[S:15][CH2:14][C@H:13]([OH:16])[O:12]1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:17]([O:19][C:20](Cl)=[O:21])[CH3:18]>N1C=CC=CC=1>[C:1]([O:9][CH2:10][C@H:11]1[S:15][CH2:14][C@H:13]([O:16][C:20]([O:19][CH2:17][CH3:18])=[O:21])[O:12]1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 10928Ethyl chloroformateHCID 69435312HCID 69435312, compound

Product 1

HCID 69945511HCID 69945511, compoundYield 73.3%

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

A mixture of cis and trans 2-benzoyloxymethyl-5-hydroxy-1,3-oxathiolane 1.49 g (6.6 mmol) (as prepared in Example 1) was reacted with ethylchloroformate 1.3 mL (13.2 mmol) and pyridine (3.3 mL) as described in example 2 to give 1.51 g of the title compound.

Sources & evidence

ORD record
ord-efa51da0856c4aeba2f0508082ba8889
Source dataset
uspto-grants-2004_12
Patent number
US06831174B2

Reaction notes

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