HRID2307574

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID11430

Potassium Carbonate

CK2O3

结构：O=C(OCc1ccc(CBr)cc1COC(=O)c1ccccc1)c1ccccc1

HCID22345618

未命名化合物

HCID22606920

未命名化合物

PRODUCTS

生成物

结构：CCC(=O)c1cc(-c2cccc(OCc3ccc(COC(=O)c4ccccc4)c(COC(=O)c4ccccc4)c3)c2)cs1

HCID22606864

未命名化合物

PROCEDURE

实验过程

In a manner similar to that of Example 1(i), by reaction of 3.8 g (16.3 mmol) of 1-[4-(3-hydroxyphenyl)-2-thiophenyl]-1-propanone with 16.9 g (18 mmol) of 3,4-bis(benzoyloxymethyl)benzyl bromide and 2.36 g (17 mmol) of potassium carbonate, the desired product is obtained in the form of white crystals (m.p.=117° C.; m=9.1 g; Y=95%).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-52eee35f648b459cae73ff67b35e8a1b
来源数据集: uspto-grants-2004_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06831106B1
来源说明: uspto-grants-2004_12

反应 SMILES

[OH:1][C:2]1[CH:3]=[C:4]([C:8]2[CH:9]=[C:10]([C:13](=[O:16])[CH2:14][CH3:15])[S:11][CH:12]=2)[CH:5]=[CH:6][CH:7]=1.[C:17]([O:25][CH2:26][C:27]1[CH:28]=[C:29]([CH:32]=[CH:33][C:34]=1[CH2:35][O:36][C:37](=[O:44])[C:38]1[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=1)[CH2:30]Br)(=[O:24])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1.C(=O)([O-])[O-].[K+].[K+]>>[C:18]1([C:17]([O:25][CH2:26][C:27]2[CH:28]=[C:29]([CH:32]=[CH:33][C:34]=2[CH2:35][O:36][C:37]([C:38]2[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=2)=[O:44])[CH2:30][O:1][C:2]2[CH:3]=[C:4]([C:8]3[CH:9]=[C:10]([C:13](=[O:16])[CH2:14][CH3:15])[S:11][CH:12]=3)[CH:5]=[CH:6][CH:7]=2)=[O:24])[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1