Aluminium lithium hydride → HCID 22606878, compound

HRID 2307579Notes

Reaction equation

HRID 2307579 reaction equation
[CH2:1]([C:3]([C:7]1[CH:12]=[CH:11][C:10]([C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([CH2:19][O:20][C:21]3[CH:22]=[C:23]([C:31](OC)=[O:32])[C:24](=[CH:29][CH:30]=3)[C:25](OC)=[O:26])[CH:14]=2)=[C:9]([CH3:35])[CH:8]=1)([OH:6])[CH2:4][CH3:5])[CH3:2].[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[CH2:1]([C:3]([C:7]1[CH:12]=[CH:11][C:10]([C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([CH2:19][O:20][C:21]3[CH:30]=[CH:29][C:24]([CH2:25][OH:26])=[C:23]([CH2:31][OH:32])[CH:22]=3)[CH:14]=2)=[C:9]([CH3:35])[CH:8]=1)([OH:6])[CH2:4][CH3:5])[CH3:2]

Participants

3

Reactant 2

HCID 21226445Aluminium lithium hydrideHCID 69929148HCID 69929148, compound

Product 1

HCID 22606878HCID 22606878, compound

Procedure

In a manner similar to that of Example 20(e), by reaction of 1.5 g (3.15 mmol) of dimethyl 4-[4′(1-ethyl-1-hydroxypropyl)-2′-methylbiphenyl-3-ylmethoxy)-phthalate with 480 mg (12.6 mmol) of lithium aluminium hydride, the desired product is obtained in the form of a white solid (m.p.=87° C.; m=1.03 g; Y=78%).

Sources & evidence

ORD record
ord-af38f99d9f5a45dc9fe55f1d9f0b5947
Source dataset
uspto-grants-2004_12
Patent number
US06831106B1

Reaction notes

Loading…