Aluminium lithium hydride → HCID 69825607, compound

HRID 2307580Notes

Reaction equation

HRID 2307580 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([C:8](=[O:11])[CH2:9][CH3:10])[CH:5]=[CH:4][C:3]=1[C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([CH2:18][O:19][C:20]2[CH:21]=[C:22]([C:30](OC)=[O:31])[C:23](=[CH:28][CH:29]=2)[C:24](OC)=[O:25])[CH:13]=1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[OH:31][CH2:30][C:22]1[CH:21]=[C:20]([CH:29]=[CH:28][C:23]=1[CH2:24][OH:25])[O:19][CH2:18][C:14]1[CH:13]=[C:12]([C:3]2[CH:4]=[CH:5][C:6]([CH:8]([OH:11])[CH2:9][CH3:10])=[CH:7][C:2]=2[CH3:1])[CH:17]=[CH:16][CH:15]=1

Participants

3

Reactant 2

HCID 21226445Aluminium lithium hydrideHCID 22606873HCID 22606873, compound

Product 1

HCID 69825607HCID 69825607, compound

Procedure

In a manner similar to that of Example 20(e), by reaction of 900 mg (2 mmol) of dimethyl 4-(2′-methyl-4′-propionylbiphenyl-3-ylmethoxy)phthalate (described in Example 22(f)) with 300 mg (8 mmol) of lithium aluminium hydride, the desired product is obtained in the form of a white solid (m.p.=78° C.; m=737 mg; Y=94%).

Sources & evidence

ORD record
ord-d9df7ae9be784ba784d13b47ec5eb435
Source dataset
uspto-grants-2004_12
Patent number
US06831106B1

Reaction notes

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