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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2307643Generated: October 30, 2026

4'-Trifluoromethyl-biphenyl-3-carbaldehyde → N-[(1S)-1,2,3,4-tetrahydro-1-naphthalenyl]-N-{[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]methyl}amine

https://huagongshe.com/reaction/2307643

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4'-Trifluoromethyl-biphenyl-3-carbaldehydeHCID 2782711—
Reactant1-Aminotetralin, (S)-HCID 7058074—
ProductN-[(1S)-1,2,3,4-tetrahydro-1-naphthalenyl]-N-{[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]methyl}amineHCID 69722555—

Reaction Steps

4′-(Trifluoromethyl)[1,1′-biphenyl]-3-carbaldehyde and (1S)-1,2,3,4-tetrahydro-1-naphthalenylamine were processed as described in Example 1A to provide the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06831193B2
Source datasetuspto-grants-2004_12
ORD IDord-7060e26b6a1f4ae7bf331c0a2a69e906
Source noteuspto-grants-2004_12