3-Hydroxybenzaldehyde → 4-(3-Formylphenoxy)benzonitrile

HRID 2307661Notes

Reaction equation

F[C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][CH:3]=1.[OH:10][C:11]1[CH:12]=[C:13]([CH:16]=[CH:17][CH:18]=1)[CH:14]=[O:15]>>[CH:14]([C:13]1[CH:12]=[C:11]([CH:18]=[CH:17][CH:16]=1)[O:10][C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][CH:3]=1)=[O:15]

Participants

Reactant 2

HCID 1013-Hydroxybenzaldehyde

HCID 145174-Fluorobenzonitrile

Product 1

HCID 132385404-(3-Formylphenoxy)benzonitrile

Procedure

4-Fluorobenzonitrile and 3-hydroxybenzaldehyde were processed as described in Example 48A to provide the title compound.

Sources & evidence

ORD record: ord-17103f34a8754b968cd39b5edb092bf4
Source dataset: uspto-grants-2004_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06831193B2

Reaction notes

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