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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2307792Generated: November 1, 2026

2-Amino-4-chloropyrimidine → HCID 69917682, compound

https://huagongshe.com/reaction/2307792

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-4-chloropyrimidineHCID 223332—
Reactant(1S)-[2-[5-(3-amino-phenyl)-pyridin-3-yloxy]-1-(1h-indol-3-ylmethyl)-ethyl]-carbamic acid tert-butyl esterHCID 69918507—
SolventEthanolHCID 702—
ProductHCID 69917682HCID 69917682—

Reaction Conditions

Temperature80 °C

Reaction Steps

A mixture of Example 121A (0.07 g, 0.153 mmol) and 4-chloro-2-pyrimidinylamine (0.021 g, 0.163 mmol) was dissolved in EtOH (1 mL). The mixture was heated to 80° C. overnight then cooled and evaporated. The product was used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06831175B2
Source datasetuspto-grants-2004_12
ORD IDord-c29fc9ef014f4fab88ef18c21893af61
Source noteuspto-grants-2004_12