5-{5-[1-Azidomethyl-2-(1h-indol-3-yl)-ethoxy]-pyridin-3-yl}-3-methyl-indazole-1-carboxylic acid tert-butyl ester → HCID 69917680, compound

Participants

Reaction Steps

To a solution of Example 406A (480 mg) in ethanol was added 10% Pd/C (160 mg) under nitrogen. This suspension was purged with hydrogen (3 circles) and was stirred under hydrogen (balloon) for 4 h. The solid material was filtered off and the filtrate was concentrated to give the desired product (443 mg, 97%). MS (APCI) m/z 498 (M+1)+.

Provenance & Evidence