3-Bromopyridine → HCID 53932144, compound

HRID 2307859Notes

Reaction equation

HRID 2307859 reaction equation
[NH:1]1[CH2:5][CH2:4][CH:3]([NH:6][C:7](=[O:13])[O:8][C:9]([CH3:12])([CH3:11])[CH3:10])[CH2:2]1.Br[C:15]1[CH:16]=[N:17][CH:18]=[CH:19][CH:20]=1>>[N:17]1[CH:18]=[CH:19][CH:20]=[C:15]([N:1]2[CH2:5][CH2:4][CH:3]([NH:6][C:7](=[O:13])[O:8][C:9]([CH3:10])([CH3:12])[CH3:11])[CH2:2]2)[CH:16]=1

Participants

3

Reactant 2

HCID 122863-BromopyridineHCID 2757234tert-butyl N-(pyrrolidin-3-yl)carbamate

Product 1

HCID 53932144HCID 53932144, compoundYield 67.2%

Procedure

tert-Butyl 3-pyrrolidinylcarbamate (0.099 g, 0.53 mmol; TCI) and 3-bromopyridine (0.050 mL, 0.52 mmol; Aldrich) were processed according to the procedure of Example 1A to provide the title compound (0.092 g, 66%). MS (CI/NH3) m/z 264 (M+H)+.

Sources & evidence

ORD record
ord-22c50d96a40e48fe89d82c529fe13104
Source dataset
uspto-grants-2004_12
Patent number
US06833370B1

Reaction notes

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