Sodium hydride → HCID 21912359, compound

HRID 2307985Notes

Reaction equation

[CH3:1][C:2]1[C:3]([O:13][C:14]2[C:19]([CH3:20])=[CH:18][C:17]([CH3:21])=[CH:16][C:15]=2[CH3:22])=[N:4][C:5]([CH3:12])=[CH:6][C:7]=1[CH:8]([OH:11])[CH2:9][CH3:10].[H-].[Na+]>>[CH2:1]([O:11][CH:8]([C:7]1[CH:6]=[C:5]([CH3:12])[N:4]=[C:3]([O:13][C:14]2[C:19]([CH3:20])=[CH:18][C:17]([CH3:21])=[CH:16][C:15]=2[CH3:22])[C:2]=1[CH3:1])[CH2:9][CH3:10])[CH2:2][CH2:7][CH3:6]

Participants

Reactant 2

HCID 24758Sodium hydride

HCID 21912322HCID 21912322, compound

Product 1

HCID 21912359HCID 21912359, compound

Procedure

The title compound was prepared by reacting of 1-[3,6-Dimethyl-2-(2,4,6-trimethyl-phenoxy)-pyridin-4-yl]-propan-1-ol with sodium hydride, followed by quenching with butyl iodide.

Workup

customby quenching with butyl iodide

Sources & evidence

ORD record: ord-d4a3a5f9fca540f7a52d34d1794d2abb
Source dataset: uspto-grants-2004_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06833378B2

Reaction notes

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