HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → 2-(4-Chloro-2,6-dimethyl-phenoxy)-4-(S,S)-(1-ethyl-2-methylamino-propylamino)-6-methyl-nicotinic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 2-(4-Chloro-2,6-dimethyl-phenoxy)-4-(1-ethyl-2-oxo-propylamino)-6-methyl-nicotinic acid methyl ester | HCID 69587539 | — |
| Product | 2-(4-Chloro-2,6-dimethyl-phenoxy)-4-(S,S)-(1-ethyl-2-methylamino-propylamino)-6-methyl-nicotinic acid methyl ester | HCID 69899528 | — |
Reaction Steps
The title compound was prepared by a reductive amination as shown above starting with 2-(4-Chloro-2,6-dimethyl-phenoxy)-4-(1-ethyl-2-oxo-propylamino)-6-methyl-nicotinic acid methyl ester and methyl amine. APCl M+1 [420.2], 1H NMR(CDCl3)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06833378B2 |
| Source dataset | uspto-grants-2004_12 |
| ORD ID | ord-465029b0f46c4d0a8767cf2773ca59b7 |
| Source note | uspto-grants-2004_12 |