反应详情

温度

75 °C

Into a reactor, 1,3-propanediol (46.7 g) and potassium hydroxide (34.5 g) were charged and stirred, and heated at the internal temperature of 75° C. for 30 minutes. At the internal temperature of 80° C., CH2═CH(CH2)2OTs (69.5 g) obtained in EXAMPLE 3-1 was added thereto over 3 hours and standed as it is after stirring for 1 hour. The reaction mixture was poured into water (250 ml) and neutralized by adding hydrochloric acid. After filtration, the filtrate was extracted with t-butyl methyl ether (300 ml) four times. The organic layer put together was dried over magnesium sulfate and subjected to filtration, and the solvent was distilled off to obtain 5.5 g of CH2═CH(CH2)2O(CH2)3OH.

1. stirringafter stirring for 1 hour
2. filtrationAfter filtration
3. extractionthe filtrate was extracted with t-butyl methyl ether (300 ml) four times
4. dry with materialThe organic layer put together was dried over magnesium sulfate
5. filtrationsubjected to filtration
6. distillationthe solvent was distilled off