4-Chlorobenzyl mercaptan → HCID 86593384, compound

HRID 2308045Notes

Reaction equation

HRID 2308045 reaction equation
[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[C:9]#[CH:10].[Cl:11][C:12]1[CH:19]=[CH:18][C:15]([CH2:16][SH:17])=[CH:14][CH:13]=1.[Na]>>[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1/[CH:9]=[CH:10]\[CH:16]([S:17][CH:16](/[CH:10]=[CH:9]\[C:3]1[CH:4]=[CH:5][C:6]([F:8])=[CH:7][C:2]=1[F:1])[C:15]1[CH:18]=[CH:19][C:12]([Cl:11])=[CH:13][CH:14]=1)[C:15]1[CH:18]=[CH:19][C:12]([Cl:11])=[CH:13][CH:14]=1

Participants

4

Reactant 3

HCID 804094-Chlorobenzyl mercaptanHCID 50638201-Ethynyl-2,4-difluorobenzeneHCID 5360545Sodium

Product 1

HCID 86593384HCID 86593384, compound

Procedure

A solution of 2,4-difluorophenylacetylene (0.02 mol), 4-chlorobenzyl mercaptan (0.02 mol) and metallic sodium (0.02 g atom) is subjected to the General Procedure to form (Z)-2,4-difluorostyryl-4-chlorobenzylsulfide. The title compound is obtained following oxidation of the sulfide, according to the General Procedure.

Sources & evidence

ORD record
ord-dc37e892a973401c8b4f0a56497e3824
Source dataset
uspto-grants-2004_12
Patent number
US06833480B2

Reaction notes

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