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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2308194Generated: October 27, 2026

3-Chloroaniline → (3-Chlorophenyl)-(7-methoxymethyl-[1,4]-dioxano[2,3-g]quinazolin-4-yl)-amine

https://huagongshe.com/reaction/2308194

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-ChloroanilineHCID 7932—
Reactant4-Chloro-7-methoxy methyl-[1,4]dioxano[2,3-g]quinazolineHCID 11161454—
Product(3-Chlorophenyl)-(7-methoxymethyl-[1,4]-dioxano[2,3-g]quinazolin-4-yl)-amineHCID 2074742563%

Reaction Steps

The titled compound (25 mg, 63%, m.p. 277-282° C.) was prepared in a similar manner as in Example 8, except for employing 4-chloro-7-methoxymethyl-[1,4]dioxano[2,3-g]quinazoline (30 mg, 0.113 mmol) and 3-chloroaniline (28 mg, 0.226 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06835735B2
Source datasetuspto-grants-2004_12
ORD IDord-0881f22e7df74197bb34932533015162
Source noteuspto-grants-2004_12