HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenamine, 3,5-bis(trifluoromethyl)- → [3,5-Bis(trifluoromethyl) phenyl]-(7-methoxymethyl-[1,4]-dioxano[2,3-g]quinazolin-4-yl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenamine, 3,5-bis(trifluoromethyl)- | HCID 9480 | — |
| Reactant | 4-Chloro-7-methoxy methyl-[1,4]dioxano[2,3-g]quinazoline | HCID 11161454 | — |
| Product | [3,5-Bis(trifluoromethyl) phenyl]-(7-methoxymethyl-[1,4]-dioxano[2,3-g]quinazolin-4-yl)-amine | HCID 20747424 | 50% |
Reaction Steps
The titled compound (8 mg, 50%) was prepared in a similar manner as in Example 8, except for employing 4-chloro-7-methoxymethyl-[1,4]dioxano[2,3-g]quinazoline (10 mg, 0.037 mmol) and 3,5-bis(trifluoromethyl)aniline (17 mg, 0.075 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06835735B2 |
| Source dataset | uspto-grants-2004_12 |
| ORD ID | ord-cb01d5815dce45d5b8978b883cb3474f |
| Source note | uspto-grants-2004_12 |