反应详情

A solution of 4-nitro-3-trifluoromethylanisole (26 g, 120 mmol) in ethyl acetate (250 mL) was hydrogenated over 10% palladium on carbon (5.3 g) at 50 psi for 1.5 h. At this time, the solution was filtered through Celite and washed with ethyl acetate (250 mL). The filtrate was concentrated in vacuo to give the title compound (22 g, 97%) as an amber oil which was pure enough for further use.

1. filtrationAt this time, the solution was filtered through Celite
2. washwashed with ethyl acetate (250 mL)
3. concentrationThe filtrate was concentrated in vacuo