HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-2-chloroanisole → 3-Chloro-4-methoxybenzeneboronic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-2-chloroanisole | HCID 3016537 | — |
| Reactant | 4-Methoxy-2-(trifluoromethyl)phenylboronic acid | HCID 12109460 | — |
| Product | 3-Chloro-4-methoxybenzeneboronic acid | HCID 3247522 | 62% |
Reaction Steps
Starting from 4-bromo-2-chloroanisole (5.0 g, 23 mmol) in place of 4-bromo-3-trifluoromethylanisole, the title compound (2.6 g, 62%) was synthesized in essentially the same manner as described above for 4-methoxy-2-trifluoromethylphenylboronic acid in Step 2, Scheme 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06835745B2 |
| Source dataset | uspto-grants-2004_12 |
| ORD ID | ord-0f37c613bc7b4a798c30b2dc681f9d34 |
| Source note | uspto-grants-2004_12 |