HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Chloroperbenzoic acid → m-Chloroperbenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Chloroperbenzoic acid | HCID 70297 | — |
| Reactant | 3-Dichloromethylsulfinyl-7-fluoro-1-methyl-4-quinolone | HCID 10380537 | — |
| Reactant | 3-Dichloromethylthio-7-fluoro-1-methyl-4-quinolone | HCID 11323779 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | m-Chloroperbenzoic acid | HCID 70297 | — |
| Product | 3-Dichloromethylsulfinyl-7-fluoro-1-methyl-4-quinolone | HCID 10380537 | — |
| Product | 3-Chloromethylthio-7-fluoro-1-methyl-4-quinolone | HCID 10445208 | — |
Reaction Steps
In another embodiment, the present invention contemplates a method for the synthesis so of 3-dichloromethylsulfinyl-7-fluoro-1-methyl-4-quinolone (dichloroflosequinan) comprising: a) providing, i) 3-dichloromethylthio-7-fluoro-1-methyl-4-quinolone, ii) dichloromethane (DCM), and iii) m-chloroperbenzoic acid (MCPBA); and b) reacting, i) 3-chloromethylthio-7-fluoro-1-methyl-4-quinolone, ii) dichloromethane (DCM), and iii) m-chloroperbenzoic acid (“MCPBA”) under conditions such that 3-dichloromethylsulfinyl-7-fluoro-1-methyl-4-quinolone is produced.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06835836B2 |
| Source dataset | uspto-grants-2004_12 |
| ORD ID | ord-140201a26f894c01ab5126a1cf97b9c4 |
| Source note | uspto-grants-2004_12 |