Piperazine → HCID 20150160, compound

HRID 2308625Notes

Reaction equation

HRID 2308625 reaction equation
Cl[C:2]1[N:3]=[C:4]([N:19]2[CH2:24][CH2:23][O:22][CH2:21][CH2:20]2)[C:5]2[N:11]=[CH:10][N:9]=[C:8]([S:12][CH:13]3[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]3)[C:6]=2[N:7]=1.[NH:25]1[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]1>>[CH:13]1([S:12][C:8]2[C:6]3[N:7]=[C:2]([N:25]4[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]4)[N:3]=[C:4]([N:19]4[CH2:24][CH2:23][O:22][CH2:21][CH2:20]4)[C:5]=3[N:11]=[CH:10][N:9]=2)[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]1

Participants

3

Reactant 2

HCID 4837PiperazineHCID 20150126HCID 20150126, compound

Product 1

HCID 20150160HCID 20150160, compound

Procedure

This compound was prepared analogous to Example 1 from 2-chloro-8-cyclohexylthio-4-morpholino-pyrimido-[5,4-d]-pyrimidine (m.p.: 179°-181° C.) and piperazine.

Sources & evidence

ORD record
ord-687fb42bcd7c4a11a4cc58e0561ffeb1
Source dataset
uspto-grants-1987_09
Patent number
US04690923

Reaction notes

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