Piperazine → HCID 20150197, compound

HRID 2308635Notes

Reaction equation

HRID 2308635 reaction equation
Cl[C:2]1[N:3]=[C:4]([N:20]2[CH2:25][CH2:24][O:23][CH2:22][CH2:21]2)[C:5]2[N:11]=[CH:10][N:9]=[C:8]([S:12][CH2:13][CH2:14][N:15]([CH2:18][CH3:19])[CH2:16][CH3:17])[C:6]=2[N:7]=1.[NH:26]1[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]1>>[CH2:16]([N:15]([CH2:18][CH3:19])[CH2:14][CH2:13][S:12][C:8]1[C:6]2[N:7]=[C:2]([N:26]3[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]3)[N:3]=[C:4]([N:20]3[CH2:25][CH2:24][O:23][CH2:22][CH2:21]3)[C:5]=2[N:11]=[CH:10][N:9]=1)[CH3:17]

Participants

3

Reactant 2

HCID 4837PiperazineHCID 20150143HCID 20150143, compound

Product 1

HCID 20150197HCID 20150197, compound

Procedure

This compound was prepared analogous to Example 2 from 2-chloro-8-(2-diethylamino-ethylthio)-4-morpholino-pyrimido-[5,4-d]-pyrimidine (resin) and piperazine.

Sources & evidence

ORD record
ord-48fe0e85e09e49f5a4c196e3c3aa14a9
Source dataset
uspto-grants-1987_09
Patent number
US04690923

Reaction notes

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