Piperazine → HCID 20150289, compound

HRID 2308642Notes

Reaction equation

[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][C:9]2[C:14]3[N:15]=[C:16](Cl)[N:17]=[C:18]([N:19]4[CH2:24][CH2:23][O:22][CH2:21][CH2:20]4)[C:13]=3[N:12]=[CH:11][N:10]=2)=[CH:4][CH:3]=1.[NH:26]1[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]1>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][C:9]2[C:14]3[N:15]=[C:16]([N:26]4[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]4)[N:17]=[C:18]([N:19]4[CH2:24][CH2:23][O:22][CH2:21][CH2:20]4)[C:13]=3[N:12]=[CH:11][N:10]=2)=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 4837Piperazine

HCID 20150142HCID 20150142, compound

Product 1

HCID 20150289HCID 20150289, compound

Procedure

This compound was prepared analogous to Example 1 from 8-(4-bromophenyl-thio)-2-chloro-4-morpholino-pyrimido-[5,4-d]-pyrimidine (m.p.: 205°-207° C.) and piperazine.

Sources & evidence

ORD record: ord-b7bce6863ac145988c71a43bd353d920
Source dataset: uspto-grants-1987_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04690923

Reaction notes

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