Piperazine → HCID 20150144, compound

HRID 2308643Notes

Reaction equation

HRID 2308643 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][C:9]2[C:14]3[N:15]=[C:16](Cl)[N:17]=[C:18]([N:19]4[CH2:24][CH2:23][S:22](=[O:25])[CH2:21][CH2:20]4)[C:13]=3[N:12]=[CH:11][N:10]=2)=[CH:4][CH:3]=1.[NH:27]1[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]1>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][C:9]2[C:14]3[N:15]=[C:16]([N:27]4[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]4)[N:17]=[C:18]([N:19]4[CH2:24][CH2:23][S:22](=[O:25])[CH2:21][CH2:20]4)[C:13]=3[N:12]=[CH:11][N:10]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 4837PiperazineHCID 13043386HCID 13043386, compound

Product 1

HCID 20150144HCID 20150144, compound

Procedure

This compound was prepared analogous to Example 1 from 8-(4-bromophenyl-thio)-2-chloro-4-(1-oxido-thiomorpholino)-pyrimido-[5,4-d]-pyrimidine (m.p.: 272°-275° C.) and piperazine.

Sources & evidence

ORD record
ord-9749666e9c894296b0dd2a2c1314860e
Source dataset
uspto-grants-1987_09
Patent number
US04690923

Reaction notes

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