Piperazine → HCID 20150254, compound

HRID 2308651Notes

Reaction equation

HRID 2308651 reaction equation
Cl[C:2]1[N:3]=[C:4]([N:22]2[CH2:27][CH2:26][S:25](=[O:28])[CH2:24][CH2:23]2)[C:5]2[N:11]=[CH:10][N:9]=[C:8]([S:12][CH2:13][C:14]3[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][CH:15]=3)[C:6]=2[N:7]=1.[NH:29]1[CH2:34][CH2:33][NH:32][CH2:31][CH2:30]1>>[CH3:21][O:20][C:17]1[CH:18]=[CH:19][C:14]([CH2:13][S:12][C:8]2[C:6]3[N:7]=[C:2]([N:29]4[CH2:34][CH2:33][NH:32][CH2:31][CH2:30]4)[N:3]=[C:4]([N:22]4[CH2:27][CH2:26][S:25](=[O:28])[CH2:24][CH2:23]4)[C:5]=3[N:11]=[CH:10][N:9]=2)=[CH:15][CH:16]=1

Participants

3

Reactant 2

HCID 4837PiperazineHCID 13043432HCID 13043432, compound

Product 1

HCID 20150254HCID 20150254, compound

Procedure

This compound was prepared analogous to Example 1 from 2-chloro-8-(4-methoxybenzyl-thio)-4-(1-oxido-thiomorpholino)-pyrimido-[5,4-d]-pyrimidine (m.p.: 217°-219° C.) and piperazine.

Sources & evidence

ORD record
ord-028f559cebee40498cff2dd29dfbc42b
Source dataset
uspto-grants-1987_09
Patent number
US04690923

Reaction notes

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