Piperazine → HCID 20150238, compound

HRID 2308656Notes

Reaction equation

Cl[C:2]1[N:3]=[C:4]([N:24]2[CH2:29][CH2:28][O:27][CH2:26][CH2:25]2)[C:5]2[N:11]=[CH:10][N:9]=[C:8]([S:12][CH2:13][C:14]3[C:23]4[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=4)[CH:17]=[CH:16][CH:15]=3)[C:6]=2[N:7]=1.[NH:30]1[CH2:35][CH2:34][NH:33][CH2:32][CH2:31]1>>[O:27]1[CH2:28][CH2:29][N:24]([C:4]2[C:5]3[N:11]=[CH:10][N:9]=[C:8]([S:12][CH2:13][C:14]4[C:23]5[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=5)[CH:17]=[CH:16][CH:15]=4)[C:6]=3[N:7]=[C:2]([N:30]3[CH2:35][CH2:34][NH:33][CH2:32][CH2:31]3)[N:3]=2)[CH2:25][CH2:26]1

Participants

Reactant 2

HCID 4837Piperazine

HCID 20150226HCID 20150226, compound

Product 1

HCID 20150238HCID 20150238, compound

Procedure

This compound was prepared analogous to Example 1 from 2-chloro-4-morpholino-8-(1-naphthylmethyl-thio)-pyrimido[5,4-d]-pyrimidine (m.p.: 206°-209° C.) and piperazine.

Sources & evidence

ORD record: ord-eeb7e425f80c437a9cbb26ba18174946
Source dataset: uspto-grants-1987_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04690923

Reaction notes

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