Piperazine → HCID 20150225, compound

HRID 2308657Notes

Reaction equation

HRID 2308657 reaction equation
Cl[C:2]1[N:3]=[C:4]([N:24]2[CH2:29][CH2:28][S:27](=[O:30])[CH2:26][CH2:25]2)[C:5]2[N:11]=[CH:10][N:9]=[C:8]([S:12][CH2:13][C:14]3[C:23]4[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=4)[CH:17]=[CH:16][CH:15]=3)[C:6]=2[N:7]=1.[NH:31]1[CH2:36][CH2:35][NH:34][CH2:33][CH2:32]1>>[C:14]1([CH2:13][S:12][C:8]2[C:6]3[N:7]=[C:2]([N:31]4[CH2:36][CH2:35][NH:34][CH2:33][CH2:32]4)[N:3]=[C:4]([N:24]4[CH2:29][CH2:28][S:27](=[O:30])[CH2:26][CH2:25]4)[C:5]=3[N:11]=[CH:10][N:9]=2)[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[CH:17]=[CH:16][CH:15]=1

Participants

3

Reactant 2

HCID 4837PiperazineHCID 13043379HCID 13043379, compound

Product 1

HCID 20150225HCID 20150225, compound

Procedure

This compound was prepared analogous to Example 1 from 2-chloro-8-(1-naphthylmethyl-thio)-4-(1-oxido-thiomorpholino)-pyrimido-[5,4-d]-pyrimidine (m.p.: 212°-215° C.) and piperazine.

Sources & evidence

ORD record
ord-3e98739bdac743b2aabcf5d850814d70
Source dataset
uspto-grants-1987_09
Patent number
US04690923

Reaction notes

Loading…