Piperazine → HCID 20150285, compound

HRID 2308659Notes

Reaction equation

HRID 2308659 reaction equation
Cl[C:2]1[N:3]=[C:4]([N:19]2[CH2:24][CH2:23][S:22](=[O:25])[CH2:21][CH2:20]2)[C:5]2[N:11]=[CH:10][N:9]=[C:8]([S:12][CH2:13][C:14]3[O:18][CH:17]=[CH:16][CH:15]=3)[C:6]=2[N:7]=1.[NH:26]1[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]1>>[CH2:13]([S:12][C:8]1[C:6]2[N:7]=[C:2]([N:26]3[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]3)[N:3]=[C:4]([N:19]3[CH2:24][CH2:23][S:22](=[O:25])[CH2:21][CH2:20]3)[C:5]=2[N:11]=[CH:10][N:9]=1)[C:14]1[O:18][CH:17]=[CH:16][CH:15]=1

Participants

3

Reactant 2

HCID 4837PiperazineHCID 13043374HCID 13043374, compound

Product 1

HCID 20150285HCID 20150285, compound

Procedure

This compound was prepared analogous to Example 1 from 2-chloro-8-(furfuryl-thio)-4-(1-oxido-thiomorpholino)-pyrimido-[5,4-d]-pyrimidine (m.p: 173°-175° C.) and piperazine.

Sources & evidence

ORD record
ord-904a81661f3b46f5b391ee9fd90f18e3
Source dataset
uspto-grants-1987_09
Patent number
US04690923

Reaction notes

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